O’Neal Comprehensive Cancer Center
Birmingham, Alabama · Comprehensive cancer center- "allows for non-UAB patients, physicians and clinicians to request an online second opinion from UAB Medicine specialists"
- New patients: 205-801-9034
More options
Second opinions from NCI cancer centers
A second opinion is normal, and most insurance covers one. These are the NCI-designated centers that offer them, from home or in person.
Your file, ready to send
Every center starts from the same things. If your reports are saved with OpenCare, My record puts the plan and every report page, in date order, into one PDF with this list on top.
Make my second-opinion file- Your medical records and reports (Dana-Farber, Cleveland Clinic, Johns Hopkins, MSK)
- The pathology report and the pathology slides (MSK, MD Anderson, Johns Hopkins)
- The scans themselves on a disc or by upload, not only the written scan reports (Dana-Farber, Johns Hopkins, Mass General Brigham)
- Your questions for the expert; Dana-Farber allows three (Dana-Farber, Mass General Brigham)
- Your treating oncologist's involvement, where the center requires it (Mass General Brigham)
From home
These centers review your records and slides and write an opinion, without a visit.
Jonsson Comprehensive Cancer Center
Los Angeles, California · Comprehensive cancer center- "You can meet with experts from the comfort of your own home, even if you're out of state."
- New patients: 888-662-8252
Moores Comprehensive Cancer Center
San Diego, California · Comprehensive cancer center- "Depending on your diagnosis and your geographic location, you may be able to receive a second opinion without leaving home."
- New patients: 858-822-6100
Stanford Cancer Institute (SCI)
Palo Alto, California · Comprehensive cancer center- "Getting a second opinion from us is easy, convenient, and all done remotely. You don’t have to visit our hospital or one of our clinics for this service."
- New patients: 833-444-7622
UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, California · Comprehensive cancer center- "Submit your medical records and receive a written second opinion. This is done remotely and for a flat fee."
- New patients: 888-689-8273
University of Colorado Cancer Center
Aurora, Colorado · Comprehensive cancer center- "Access UCHealth University of Colorado Cancer Center’s independent experts without the need to travel by participating in the UCHealth Remote Second Opinion program."
- New patients: 720-848-0300
Yale Cancer Center
New Haven, Connecticut · Comprehensive cancer center- "Through PinnacleCare VirtualConnect, you can receive a second opinion from a Yale Medicine specialty physician right in the comfort of your home."
- New patients: 1-855-4-SMILOW
Sylvester Comprehensive Cancer Center
Miami, Florida- "International patients benefit from the Same Week clinic and have the option of a second opinion or remote consultation with one of our faculty members"
- New patients: 1-844-324-HOPE (4673)
The University of Chicago Comprehensive Cancer Center
Chicago, Illinois · Comprehensive cancer center- "we welcome patients who seek second opinions for cancer care, and offer both on-site and remote second opinions."
- New patients: 1-855-702-8222
Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland · Comprehensive cancer center- "a second opinion requires only that you or your doctor send us your pathology slides, key medical records and signed paperwork requesting the opinion."
- New patients: 410-955-8964
Dana-Farber/Harvard Cancer Center
Boston, Massachusetts · Comprehensive cancer center- "The entire process is conducted online — including collecting your records — helping you avoid disruptions to your regular schedule."
- New patients: 877-442-3324
Herbert Irving Comprehensive Cancer Center
New York, New York · Comprehensive cancer center- "You can receive a written second opinion, without ever leaving home"
- New patients: 212-305-5098
Memorial Sloan-Kettering Cancer Center
New York, New York · Comprehensive cancer center- "Second opinions to confirm or change a cancer diagnosis or treatment plan, if you live in the U.S."
- New patients: 800-525-2225
Duke Cancer Institute
Durham, North Carolina · Comprehensive cancer center- New patients: 866-385-3123
The Ohio State University Comprehensive Cancer Center
Columbus, Ohio · Comprehensive cancer center- "Feel more confident and gain clarity with an online second opinion from the medical experts at The Ohio State University Wexner Medical Center."
- New patients: 1-800-293-5066
Abramson Cancer Center
Philadelphia, Pennsylvania · Comprehensive cancer center- "our team of experts offers second opinions to grant you peace of mind"
- New patients: 800-789-7366
St. Jude Children's Research Hospital
Memphis, Tennessee · Comprehensive cancer center- "We do not generally bring patients to Memphis for consultation unless those patients are likely to be eligible for St. Jude clinical trials."
- New patients: 1-888-226-4343
University of Wisconsin Carbone Cancer Center
Madison, Wisconsin · Comprehensive cancer center- "You also have the option of scheduling your second opinion visit by video if that is more convenient."
- New patients: 608-915-0100
In person
These offer second-opinion visits. Many also take records by mail first.
Mayo Clinic Cancer Center
Phoenix, Arizona · Comprehensive cancer center- "You can self-refer for a second opinion or ask your oncologist for a referral to Mayo Clinic."
- New patients: 480-301-8484
Chao Family Comprehensive Cancer Center
Orange, California · Comprehensive cancer center- "Before your second opinion appointment, your UCI Health physician will review your previous health records, imaging and test results."
- New patients: 714-456-8000
City of Hope Comprehensive Cancer Center
Duarte, California · Comprehensive cancer center- "At City of Hope, we believe you need to clearly understand your options to join your care team in making the right decisions."
- New patients: (877) 460-4673
UC Davis Comprehensive Cancer Center
Sacramento, California · Comprehensive cancer center- "we suggest you ask your insurance company if it will pay for a second opinion or consultation at UC Davis Comprehensive Cancer Center."
- New patients: 916-734-5959
USC Norris Comprehensive Cancer Center
Los Angeles, California · Comprehensive cancer center- "We remotely evaluate your medical records to give specific suggestions for your treatment plan in the U.S."
- New patients: (800) 872-2273
Georgetown Lombardi Comprehensive Cancer Center
Washington, District of Columbia · Comprehensive cancer center- "If you're looking for a second opinion on a recent cancer diagnosis, we're here for you, too, even if you live far away."
- New patients: 202-444-2223
Mayo Clinic Comprehensive Cancer Center (Jacksonville, Florida)
Jacksonville, Florida · Comprehensive cancer center- "You can self-refer for a second opinion or ask your oncologist for a referral to Mayo Clinic."
- New patients: 904-953-0853
Moffitt Cancer Center
Tampa, Florida · Comprehensive cancer center- "Our multispecialty team will review your records and diagnostic work, and then order any additional tests that might be necessary to achieve a better understanding of your situation."
- New patients: 1-888-663-3488
University of Florida Health Cancer Institute
Gainesville, Florida- "We offer specialized healthcare services, including screenings, consultations, second opinions, periodic re-evaluations and continuing care."
- New patients: (352) 265-0725
Winship Cancer Institute
Atlanta, Georgia · Comprehensive cancer center- "If you have been diagnosed with cancer or need a second opinion, we're here for you."
- New patients: 404-778-1900
Holden Comprehensive Cancer Center
Iowa City, Iowa · Comprehensive cancer center- "Holden Comprehensive Cancer Center is ready to quickly provide you with an expert second opinion to ensure you get the right care for your unique cancer."
- New patients: 319-356-4200
The University of Kansas Cancer Center
Kansas City, Kansas · Comprehensive cancer center- "Connect with one of our nurse navigators at 913-588-1227 or 844-323-1227 to schedule your cancer second opinion."
- New patients: 913-588-1227
Markey Cancer Center
Lexington, Kentucky · Comprehensive cancer center- "Second opinions are your right as a patient."
- New patients: 859-257-4488
University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center
Baltimore, Maryland · Comprehensive cancer center- "Newly Diagnosed or Seeking Second Opinions"
- New patients: 410-328-7904
The Barbara Ann Karmanos Cancer Institute
Detroit, Michigan · Comprehensive cancer center- "All second opinion patients will be offered an appointment within 7 days."
- New patients: 1-800-527-6266
University of Michigan Rogel Cancer Center
Ann Arbor, Michigan · Comprehensive cancer center- "how to get a second opinion"
- New patients: 734-647-8902
Masonic Cancer Center
Minneapolis, Minnesota · Comprehensive cancer center- "To find out how to get a second opinion, talk with your doctor or care coordinator."
- New patients: 612-676-4200
Alvin J. Siteman Cancer Center
Saint Louis, Missouri · Comprehensive cancer center- "You don’t need your doctor to refer you for a second opinion."
Fred and Pamela Buffett Cancer Center
Omaha, Nebraska- "Contact us – call 402.559.5600 for more information and to begin the process."
- New patients: 402-559-5600
Dartmouth Cancer Center
Lebanon, New Hampshire · Comprehensive cancer center- "It is your responsibility to forward all your medical records, tests, and x-rays from your first opinion to the second opinion physician or group."
- New patients: 603-650-6272
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health
New York, New York · Comprehensive cancer center- "help connect you to the right provider"
- New patients: 212-731-6000
Montefiore Einstein Cancer Center
Bronx, New York · Comprehensive cancer center- "Have a cancer diagnosis and seek a second opinion"
- New patients: 833-632-2623
Mount Sinai Tisch Cancer Center
New York, New York- "We can usually schedule second-opinion appointments for diagnosed cancers of the breast or reproductive system on the same day or within 24 hours."
- New patients: 1-844-MD-CANCER
Roswell Park Comprehensive Cancer Center
Buffalo, New York · Comprehensive cancer center- "We aim to schedule your second opinion appointment within five days, depending on medical records, insurance, and specialist availability."
- New patients: 1-800-767-9355 (1-800-ROSWELL)
Wilmot Cancer Institute
Rochester, New York- "While many new patients are referred by their doctors, a referral is not necessary to see one of our cancer specialists."
- New patients: (585) 275-5830
Wake Forest Baptist Comprehensive Cancer Center
Winston-Salem, North Carolina · Comprehensive cancer center- "Our Comprehensive Cancer Center's Second Opinion program was created to meet the needs of cancer patients seeking cancer expertise for innovative treatment options."
- New patients: 888-716-9253
Case Comprehensive Cancer Center
Cleveland, Ohio · Comprehensive cancer center- "By getting a second opinion at a NCI-designated comprehensive cancer center, you are most likely to get the most accurate diagnosis and the most comprehensive and up-to-date treatment plan."
- New patients: 1-866-844-2273
Knight Cancer Institute
Portland, Oregon · Comprehensive cancer center- "We’re happy to provide you with a second opinion so you can be confident you are getting the most accurate diagnosis and the best care possible."
- New patients: 503-494-7999
Fox Chase Cancer Center
Philadelphia, Pennsylvania · Comprehensive cancer center- "These options may be available for new patients seeking a treatment plan or a second opinion, as well as existing patients."
- New patients: 888-369-2427
Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania · Comprehensive cancer center- "Request an appointment using the form on this page, or call us at 1-800-533-3669 to schedule an in-person or telehealth appointment."
- New patients: 1-800-533-3669
UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania · Comprehensive cancer center- "If not, an expedited second opinion by one of our doctors may be a good option."
- New patients: 412-647-2811
Hollings Cancer Center
Charleston, South Carolina- "Many of our physicians also offer telehealth visits for initial consults, second opinions or follow-up care and work closely with community oncologists to coordinate care."
- New patients: 843-985-3969
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee · Comprehensive cancer center- "No matter where you are in your cancer journey, our specialists can meet with you and discuss your diagnosis and treatment."
- New patients: (615) 936-8422
Mays Cancer Center at UT Health San Antonio
San Antonio, Texas- "Our cancer specialists provide second opinions to review a diagnosis or treatment plan and discuss a variety of treatment options."
- New patients: 210-450-1000
The University of Texas MD Anderson Cancer Center
Houston, Texas · Comprehensive cancer center- "Second opinion appointments at UT MD Anderson are treated like standard new patient appointments. We do not offer remote second opinions at this time."
- New patients: 1-877-632-6789
Huntsman Cancer Institute
Salt Lake City, Utah · Comprehensive cancer center- "All patients can benefit from getting a second opinion from one of our cancer specialists."
- New patients: 801-587-7000
University of Virginia Cancer Center
Charlottesville, Virginia · Comprehensive cancer center- "We provide second opinions all the time. All you have to do is call and ask."
- New patients: 434-924-9333
VCU Massey Comprehensive Cancer Center
Richmond, Virginia · Comprehensive cancer center- "Getting a second opinion is an important way for you to participate in your health care."
- New patients: 877-462-7739
Fred Hutchinson/University of Washington/Seattle Children’s Cancer Consortium
Seattle, Washington · Comprehensive cancer center- "To request an appointment for a second opinion or patient care at Fred Hutch, please call us toll-free at 1.855.557.0555."
- New patients: 1-855-557-0555
From each center's own site, checked 22 Oct 2026. Ask your insurer whether a second opinion needs a referral, and whether the center is in your network.